The second crossover study was identical in design except that clopidogrel and omeprazole were given 12 hours apart. Findings were similar to those in the first study indicating that administering clopidogrel and omeprazole at different times does not prevent this interaction Table 1. Healthcare professionals are advised to avoid the concomitant use of clopidogrel with omeprazole and other CYP2C19 inhibitors e.
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