The mechanism of its action might be through its antioxidant and estrogenic effects on reproductive system to ameliorate the fertility parameters. RJ can potentially be considered as a treatment to promote fertility. The authors are grateful to the members of Fertility and Infertility Research Center for their helpful support. The authors declare that they have no conflict of interest. National Center for Biotechnology Information , U.
Int J Fertil Steril. Published online Oct Elham Ghanbari , M. Sc, 1 Mohammad Rasool Khazaei , Ph. D, 1 and Vahid Nejati , Ph. Author information Article notes Copyright and License information Disclaimer. Received Dec 22; Accepted Feb Copyright Any use, distribution, reproduction or abstract of this publication in any medium, with the exception of commercial purposes, is permitted provided the original work is properly cited. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
This article has been cited by other articles in PMC. Abstract Background Royal jelly RJ is a complementary diet widely prescribed by traditional medicine specialists for treatment of in- fertility. Conclusion RJ promotes folliculogensis and increases ovarian hormones.
Introduction Puberty is the underlying reproductive process, in which several maturation changes occur in the body to promote adult phenotype. Materials and Methods In this experimental study, 32 immature female Wistar rats aged about 25 days g were used for our study. Nitric oxide assay The serum levels of NO were determined colorimetrically by Griess method, which includes the conversion of nitrate to nitrite. Ovarian histology evaluation The ovaries and uteri were dissected and cleaned from fatty tissues and were weighed afterwards.
Open in a separate window. Discussion In this study, administration of different doses of RJ to immature female rats led to remarkable increase in the serum steroid hormones, and in body, uterine and ovarian weights. Conclusion Administration of RJ to immature female rats promotes follicular growth and development in their ovaries. References 1. Metabolic control of female puberty: potential therapeutic targets. Expert Opin Ther Targets. Exposure of adult rats to estradiol valerate induces ovarian cyst with early senescence of follicles.
Mol Cell Endocrinol. Proteomic analysis of the royal jelly and characterization of the functions of its derivation glands in the honeybee. J Proteome Res. Biological activities of royal jelly-review. Animal Science and Biotechnologies. Estrogenic activities of fatty acids and a sterol isolated from royal jelly.
Evid Based Complement Alternat Med. Effect of royal jelly on bisphenol A-induced proliferation of human breast cancer cells. Biosci Biotechnol Biochem. Reproductive responses following royal jelly treatment administered orally or intramuscularly into progesteronetreated Awassi ewes. Anim Reprod Sci. Reproductive responses in ewes treated with eCG or increasing doses of royal jelly. Royal jelly may improve the metabolism of glucose and redox state of ovine oocytes matured in vitro and embryonic development following in vitro fertilization.
Midcycle pericoital intravaginal bee honey and royal jelly for male factor infertility. Int J Gynecol Obstet.
Weight status in young girls and the onset of puberty. Oct 05, Rating trying to conceive naturally by: Lucky Hi, I got to know about Royal jelly bee pollen in online forums and through this site. I would really like to try this natural substance. Am trying to conceive naturally and am having thyroid and pcos.
I started consuming half a spoon daily but the problem is am feeling stomach upset and gastritis after one hour of consuming RJBP liquid. My concerns are:- is it safe to continue royal jelly and bee pollen even though i experience gastritis or stomach upset?
Will it interfere with my thyroid medication? Please suggest. However, when I received the item, the package said "Do not consume" and "For external use only" I didn't expect that! I contacted the seller and I was told that, because they are a Skincare company and don't hold a food licence, they must advise not to consume their product. Do you think it is still ok to take it as a food supplement?
Thanks, That is very odd Ana. It is likely ok but I'm not sure if you want to take the risk. I only recommend buying royal jelly from Canada as they have the strictest nutritional supplement standards in the world. I do know from experience that there is a great deal of low grade royal jelly on the market that is loaded with toxins. Jan 29, Rating I have been taking Royal jelly by: Anonymous I have not had a period for 2 months and I am trying to conceive, I am taking Royal jelly in liquid form and bee pollen I can actually feel my body healing and my periods coming back, I have every faith that these two things will help me get preg.
Jun 14, Rating Royal jelly and wobenzym n by: Anonymous Can royal jelly and wobenzym n be taken together since both have hormone changing substances for fertility?
Angela's Comments: I see no reason why you should not take them together. Should be fine. So, is that going to be better then the pills or power? Angela's comments: Not necessarily. A quality freeze dried product is just as effective as a fresh product. Mar 28, Rating Congratulations by: Angela Thank you for sharing and congratulations on your pregnancy!
Facebook Twitter. Stay Connected With Us. May 15, Rating. Feb 28, Rating. Jul 06, Rating. Thyroid medication by: Lindsay I really want to take Royal Jelly to try to help with fertility. Click here to add your own comments Join in and write your own page! Comments for Fertility Average Rating Click here to add your own comments. Aug 26, Rating. Oct 05, Rating. Jun 09, Rating. Jan 29, Rating. I have been taking Royal jelly by: Anonymous I have not had a period for 2 months and I am trying to conceive, I am taking Royal jelly in liquid form and bee pollen I can actually feel my body healing and my periods coming back, I have every faith that these two things will help me get preg.
Jun 14, Rating. Royal jelly and wobenzym n by: Anonymous Can royal jelly and wobenzym n be taken together since both have hormone changing substances for fertility? Comments for royal jelly in honey forum for fertility Average Rating Click here to add your own comments.
Jun 12, Rating. Firstly, royal jelly has nothing to do with a type of dessert eaten by kings and queens! So for bees at least, it is an important source of nutrition. If larvae are fed royal jelly exclusively for a longer period, the larvae will actually develop into a queen bee. Royal jelly is actually considered a food product. Here is where the link between royal jelly and human fertility comes in. A queen bee lives exclusively on royal jelly and this allows her to lay up to 2, eggs per day.
There are claims that the royal jelly can help balance out hormones in the bee to improve egg laying ability, and there actually may be a small amount of truth to this. But will it do the same for humans? To start off, I should say that there are no clinical studies looking at royal jelly and egg development in women so you would be taking it on faith that royal jelly will have any benefit.
But there is a small twist to the story. Royal jelly has been found to have some estrogen-like effects from its unique profile of fatty acids. Though I should stress these effects have only been seen in lab Petri dishes and mice.
Estrogen, of course, is vital for a healthy menstrual cycle so there is a small amount of plausibility to the royal jelly and fertility story. Adding to the case that royal jelly could have hormone effects was a study actually done in post-menopausal women.
Surprisingly, royal jelly showed some benefit in offering relief from menopause symptoms, but it was only anxiety and backache that improved. The story about royal jelly and hormones takes an interesting turn when you discover that it naturally contains a small amount of testosterone! And at least in infertile men , royal jelly can cause a small rise in testosterone levels.
How this could relate to women is interesting as testosterone helps develop follicles so this could help in women with a low ovarian reserve or potentially even who have a poor response to IVF. Testosterone has another side in fertility for women though.
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